Targeting of Nucleic Acids

Group members
Group members
Group members
Maria Duca
Maria Duca

Dr. Maria Duca

CNRS Research Director

Director of TNA research group

Vice-President of the French Medicinal Chemistry Society (SCT)

Audrey Di Giorgio
Audrey Di Giorgio

Dr. Audrey Di Giorgio

Assistant Professor - Université Côte d'Azur

Nadia Patino
Nadia Patino

Pr. Nadia Patino

Full Professor - Université Côte d'Azur

Stéphane Azoulay
Stéphane Azoulay

Pr. Stéphane Azoulay

Full Professor - Université Côte d'Azur

Vice-President for Education at Université Côte d'Azur

Students and Post-docs

Benjamin BOUDET, PhD (CIFRE Sanofi, 2013-2026)

Eden GUEDU, PhD (MESR, 2023-2026)

Jihed AZZOUZ, PhD (MENRT, 2021-2024)

Eleonora TESINI, PhD (Chiesi Farmaceutici, 2022-2025)

Marc Alexandre D'ELIA, IE

Kateryna DEMCHENKO, M2 student

Sofia CRESPI, M2 student


Iryna SCHECHELOVA, PhD (COFUND-H2020, 2019-2023)

Marc PANOSETTI, PhD (IIT-UCA, 2020-2023)
Now post-doc at the University of Oxford, UK in the group of Pr. Angela Russel

Sandra KOVACHKA, PhD (COFUND-H2020, 2019-2023)
Now post-doc at Scripps Institute in the group of Pr. Matthew Disney, Florida, USA

Now Research Assistant at the University of Auckland, New Zealand

Malik ZERGUINE, M2 (IDEX, 2023)
Now PhD student at the University of Oslo, Norway

Mélanie PERNAK, PhD (CIFRE Sanofi, 2019-2022)

Maurinne BONNET, PhD (MENRT, 2019-2022)
Now post-doc in Garner's lab at the Department of Medicinal Chemistry of the University of Michigan, USA

Dr. Céline MARTIN, PhD (ANR Innovantibio, 2018-2021)
Now post-doc at the Department of Chemistry and Biochemistry, University of Maryland, USA

Matthieu JORANDON, M2 (IDEX, 2022)
Now PhD student at the Institute of Chemistry of Nice, France

Sylvain POULET, PhD (IDEX UCA, 2018-2022)

Eleonora TESINI, Master 2 (University of Bologna, 2021)
Now PhD student in our group

Dr. Chloé MAUCORT, PhD (Institut de Recherche Servier, 2017-2020)
Now Project Leader at Novalix

Marc PANOSETTI, Master 2 (ANR, 2020)
now PhD student in TNA group

Alessandro MONTI, Master 2 (University of Bologna, 2020)
now PhD student at the University of Vienna (Austria)

Dr. Benjamin ZAGIEL, Post-doc (INCa, 2019-2020)
now ATER at the Univesity of Lille (France)

Samy AOUAD, Master 2 (IDEX UCA, 2019)

Dr. Klara ARADI, Post-doc (INCa, 2018)
now post-doc at Research Center for Natural Sciences, Institute of Organic Chemistry, Hungary

Dr. Anita RAYAR, Post-doc (UCA, 2017-2018)
Now scientist at Laboratoires Servier

Serena DE PICCOLI, Master 2 (UCA, 2018)
now PhD student at ISIS in Strasbourg

Dr. Thi Phuong Anh TRAN, PhD (French Embassy in Vietnam, 2013-2016)
Now teacher at Ho Chi Min University in Vietnam

Dr. Duc Duy VO, Post-doc (ANR, 2012-2014)
Now Principal Investigator at Uppsala University in Sweden

Dr. Jean-Patrick JOLY, PhD (Région PACA, 2011-2014)
Now Research Engineer at Institut de Chimie Radicalaire (ICR) in Marseille

Coralie CHARRAT, Master 2 (ANR, 2012)

Lorena ZARA, Sujet : Master 2 (2011)
now PhD student at the University of Bordeaux

Guillaume MATA, Master 2 (2010)
After a PhD at ETH in Zurich, he is now post-doc at the University of Stanford

Latest News

JMedChem 2023
JMedChem 2023

The last article from the team is now published in Journal of Medicinal Chemistry (American Chemical Society)!!!


Dr. Maria Duca will present the team's work at the EMBO workshop in Chemical Biology in September 2024 !!

Chemistry European Journal publication 2023
Chemistry European Journal publication 2023

Check our work in collaboration with APSM team published in Chemistry A European Journal and the work about De-novo design of pre-miR-21 maturation inhibitors has been performed in collaboration with Pr. Véronique Michelet team !!

TNA team's results were presented at ACSMEDI-EFMC MedChemFrontiers conference in Boston !!


The TNA article entitled Design, Synthesis, and Evaluation of Neomycin-Imidazole Conjugates for RNA Cleavage is now published in ChemPlusChem and is part of a special collection devoted to the 10th anniversary of the Institute of Chemistry of Nice !!


Dr. Maria Duca will present the team's work at the XXVII National Meeting on Medicinal Chemistry in Bari from September 11 to 14!

Bandeau ISMC
Bandeau ISMC

TNA team is organizing the XXVII EFMC International Symposium on Medicinal Chemistry in Nice from 4 to 8 of September, do not miss this great event about medicinal chemistry!

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Dr. Maria Duca will present the team's works at the French American Chemistry Symposium (FACS XVIII) next June in Charleston (USA)!
Archive of "RSC Medicinal Chemistry".
The last paper of the groupe entitled Development of 2-deoxystreptamine–nucleobase conjugates for the inhibition of oncogenic miRNA production is now published in RSC Medicinal Chemistry (Royal Society of Chemistry)









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